I didn't really notice this until updating to the latest, but there is a noticeable decrease in framerate when I have several animated sprites going on at the same time. I have maybe 10, and the profiler is saying there is an additional 4-5ms in Update() happening. This goes back to normal when I disable the animated sprites. All the animated sprites are using the same solid texture and have maybe 3 or 4 frames running on loop. These are just simple background elements.
EDIT: Testing on iPhone 4